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Bioassays, kits, and reagents used to analyze various properties of living cell samples. Products include apoptosis assays, signal transduction assays, and cell growth and differentiation assays.
Irreversible, cell permeable inhibitor of caspase-1. Inhibits also caspase-4. Alternative name: Caspase 1 inhibitor (fluoromethylketone)or. MW: 630.7. Purity: ≥99% (HPLC). Formulation: Liquid. In DMSO. Long Term Storage: -20°C.
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The R-PLEX Human Annexin A1 Assay from Meso Scale Discovery is a multiplex immunoassay that measures Annexin A1 levels in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies calibrators and diluents valid for serum EDTA plasma heparin plasma and cell culture supernatant samples The assay has a typical lower limit of detection of 0 04 ng/mL and an upper limit of quantification of 1500 ng/mL for Annexin A1
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ANXA5 also known as annexin V is a member of the annexin family of calcium-dependent phospholipid binding proteins which are involved in membrane-related activity along exocytotic and endocytotic pathways ANXA5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel properties It functions in signal transduction inflammation cell growth and differentiation ANXA5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex which is involved in the blood coagulation cascade There are at least ten different annexins in the mammalian species Annexins do not contain signal peptides yet some annexins (A1 A2 and A5) appear to be secreted in a physiologically regulated fashion The binding of labeled ANXA5 to phosphatidylserine is commonly used as a marker of apoptosis
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The KILR T2 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
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